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1cnl
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cnl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cnl RCSB], [http://www.ebi.ac.uk/pdbsum/1cnl PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cnl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cnl RCSB], [http://www.ebi.ac.uk/pdbsum/1cnl PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CXA1_CONIM CXA1_CONIM]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks mammalian neuronal nAChRs (alpha-3/beta-2 > alpha-7 > alpha-3/beta-4). Has no effect on nAChRs composed of alpha-2/beta-2, alpha-3/beta-2, alpha-4/beta-2, alpha-2/beta-4, alpha-3/beta-4, or alpha-4/beta-4 subunits. Acts voltage-independently. Is highly active against the neuromuscular receptor in frog.<ref>PMID:8206995</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 00:00, 25 December 2014
ALPHA-CONOTOXIN IMI
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