1f81
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f81 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1f81 RCSB], [http://www.ebi.ac.uk/pdbsum/1f81 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f81 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1f81 RCSB], [http://www.ebi.ac.uk/pdbsum/1f81 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CBP_MOUSE CBP_MOUSE]] Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300 (By similarity).<ref>PMID:10207073</ref> <ref>PMID:11701890</ref> <ref>PMID:15220471</ref> <ref>PMID:16287980</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] |
Revision as of 13:09, 25 December 2014
SOLUTION STRUCTURE OF THE TAZ2 DOMAIN OF THE TRANSCRIPTIONAL ADAPTOR PROTEIN CBP
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Categories: Mus musculus | Dyson, H J | Guzman, R N.De | Liu, H L | Martinez-Yamout, M | Wright, P E | Cbp | Taz2 | Transcription | Zinc finger