1hhn
From Proteopedia
(Difference between revisions)
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hhn RCSB], [http://www.ebi.ac.uk/pdbsum/1hhn PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hhn RCSB], [http://www.ebi.ac.uk/pdbsum/1hhn PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CALR_RAT CALR_RAT]] Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 20:08, 24 December 2014
CALRETICULIN P-DOMAIN
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