1w0i
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 1w0i |SIZE=350|CAPTION= <scene name='initialview01'>1w0i</scene>, resolution 2.10Å | |PDB= 1w0i |SIZE=350|CAPTION= <scene name='initialview01'>1w0i</scene>, resolution 2.10Å | ||
|SITE= <scene name='pdbsite=KAA:So4+Binding+Site+For+Chain+B'>KAA</scene> | |SITE= <scene name='pdbsite=KAA:So4+Binding+Site+For+Chain+B'>KAA</scene> | ||
| - | |LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> | + | |LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Beta-ketoacyl-acyl-carrier-protein_synthase_I Beta-ketoacyl-acyl-carrier-protein synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-acyl-carrier-protein_synthase_I Beta-ketoacyl-acyl-carrier-protein synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w0i OCA], [http://www.ebi.ac.uk/pdbsum/1w0i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1w0i RCSB]</span> | ||
}} | }} | ||
| Line 27: | Line 30: | ||
[[Category: Rasmussen, A V.]] | [[Category: Rasmussen, A V.]] | ||
[[Category: Wettstein-Knowles, P Von.]] | [[Category: Wettstein-Knowles, P Von.]] | ||
| - | [[Category: K]] | ||
| - | [[Category: SO4]] | ||
[[Category: beta-ketoacyl-(acyl carrier protein) synthase]] | [[Category: beta-ketoacyl-(acyl carrier protein) synthase]] | ||
[[Category: condensing enzyme]] | [[Category: condensing enzyme]] | ||
| Line 35: | Line 36: | ||
[[Category: synthase]] | [[Category: synthase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:29:27 2008'' |
Revision as of 21:29, 30 March 2008
| |||||||
| , resolution 2.10Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , | ||||||
| Activity: | Beta-ketoacyl-acyl-carrier-protein synthase I, with EC number 2.3.1.41 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
ARABIDOPSIS THALIANA MITOCHONDRIAL KAS
Overview
Mitochondrial fatty acid synthesis is catalyzed by a dissociated fatty acid synthase similar to those of plant plastids and bacteria. The crystal structure of a mitochondrial beta-ketoacyl-[acyl carrier protein] synthase (mtKAS), namely that from Arabidopsis thaliana, has been determined for the first time. This enzyme accomplishes the vital condensation steps in constructing fatty acid carbon skeletons. The product profile of mtKAS is unusual in that C8 and C(14-16) fatty acyl chains predominate. An enzyme architecture that likely is the basis for the observed bimodal profile of mtKAS products can be derived from the shape of the acyl binding pocket.
About this Structure
1W0I is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
Reference
Structure of the mitochondrial beta-ketoacyl-[acyl carrier protein] synthase from Arabidopsis and its role in fatty acid synthesis., Olsen JG, Rasmussen AV, von Wettstein-Knowles P, Henriksen A, FEBS Lett. 2004 Nov 5;577(1-2):170-4. PMID:15527780
Page seeded by OCA on Mon Mar 31 00:29:27 2008
