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4bfd
From Proteopedia
(Difference between revisions)
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==CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH CHEMICAL LIGAND== | ==CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH CHEMICAL LIGAND== | ||
<StructureSection load='4bfd' size='340' side='right' caption='[[4bfd]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4bfd' size='340' side='right' caption='[[4bfd]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4bfd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4bfd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BFD FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8T3:N-[3-[(1S,3S,6S)-5-AZANYL-3-METHYL-4-AZABICYCLO[4.1.0]HEPT-4-EN-3-YL]-4-FLUORANYL-PHENYL]-5-CHLORANYL-PYRIDINE-2-CARBOXAMIDE'>8T3</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8T3:N-[3-[(1S,3S,6S)-5-AZANYL-3-METHYL-4-AZABICYCLO[4.1.0]HEPT-4-EN-3-YL]-4-FLUORANYL-PHENYL]-5-CHLORANYL-PYRIDINE-2-CARBOXAMIDE'>8T3</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bek|4bek]], [[4bel|4bel]], [[4bfb|4bfb]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bek|4bek]], [[4bel|4bel]], [[4bfb|4bfb]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bfd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bfd RCSB], [http://www.ebi.ac.uk/pdbsum/4bfd PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bfd OCA], [http://pdbe.org/4bfd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bfd RCSB], [http://www.ebi.ac.uk/pdbsum/4bfd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bfd ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4bfd" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Banner, D W]] | [[Category: Banner, D W]] | ||
Revision as of 09:05, 4 August 2016
CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH CHEMICAL LIGAND
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Categories: Human | Memapsin 2 | Banner, D W | Benz, J | Stihle, M | Hydrolase
