3v71
From Proteopedia
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==Crystal structure of PUF-6 in complex with 5BE13 RNA== | ==Crystal structure of PUF-6 in complex with 5BE13 RNA== | ||
<StructureSection load='3v71' size='340' side='right' caption='[[3v71]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='3v71' size='340' side='right' caption='[[3v71]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3v71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3v71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V71 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v6y|3v6y]], [[3v74|3v74]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v6y|3v6y]], [[3v74|3v74]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">puf-7, B0273.2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">puf-7, B0273.2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v71 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v71 RCSB], [http://www.ebi.ac.uk/pdbsum/3v71 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v71 OCA], [http://pdbe.org/3v71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3v71 RCSB], [http://www.ebi.ac.uk/pdbsum/3v71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3v71 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/PUF7_CAEEL PUF7_CAEEL]] RNA-binding protein that binds to the consensus sequence 5'-CUCUGUAUCUUGU-3' in mRNA 3'-UTRs and modulates mRNA expression and stability. Functions redundantly with puf-5 and puf-6 in oocyte formation and organization, early embryonic cell divisions, and repression of expression of glp-1 and other maternal mRNAs in late oogenesis.<ref>PMID:17234175</ref> <ref>PMID:22205700</ref> <ref>PMID:22542599</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Caeel]] |
[[Category: Hall, T M.T]] | [[Category: Hall, T M.T]] | ||
[[Category: Holley, C H]] | [[Category: Holley, C H]] | ||
Revision as of 09:45, 4 August 2016
Crystal structure of PUF-6 in complex with 5BE13 RNA
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Categories: Caeel | Hall, T M.T | Holley, C H | Keles, S | Kershner, A | Kimble, J | Qiu, C | Wang, Y | Wickens, M | Wilinski, D | Puf repeat | Rna binding protein-rna complex
