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2lbu
From Proteopedia
(Difference between revisions)
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<StructureSection load='2lbu' size='340' side='right' caption='[[2lbu]], [[NMR_Ensembles_of_Models | 4 NMR models]]' scene=''> | <StructureSection load='2lbu' size='340' side='right' caption='[[2lbu]], [[NMR_Ensembles_of_Models | 4 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lbu]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2lbu]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Podas Podas]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LBU FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGO:SODIUM+3,3-(1E,1E)-BIPHENYL-4,4-DIYLBIS(DIAZENE-2,1-DIYL)BIS(4-AMINONAPHTHALENE-1-SULFONATE)'>CGO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGO:SODIUM+3,3-(1E,1E)-BIPHENYL-4,4-DIYLBIS(DIAZENE-2,1-DIYL)BIS(4-AMINONAPHTHALENE-1-SULFONATE)'>CGO</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rnm|2rnm]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rnm|2rnm]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lbu RCSB], [http://www.ebi.ac.uk/pdbsum/2lbu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbu OCA], [http://pdbe.org/2lbu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lbu RCSB], [http://www.ebi.ac.uk/pdbsum/2lbu PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/HETS_PODAS HETS_PODAS]] Responsible for heterokaryon incompatibility, a process that ensures that during spontaneous, vegetative cell fusion only compatible cells from the same colony survive (non-self-recognition). Forms a prion for the non-Mendelian trait [het-s]. Interacts with het-S from incompatible cells to trigger a lethal reaction that prevents the formation of viable heterokaryons. It is unknown if the native, soluble protein has a cellular function.<ref>PMID:1886611</ref> <ref>PMID:8224826</ref> <ref>PMID:9275200</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Podas]] |
[[Category: Aguzzi, A]] | [[Category: Aguzzi, A]] | ||
[[Category: Bockmann, A]] | [[Category: Bockmann, A]] | ||
Revision as of 22:52, 9 September 2015
HADDOCK calculated model of Congo red bound to the HET-s amyloid
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Categories: Podas | Aguzzi, A | Bockmann, A | Ernst, M | Hornemann, S | Meier, B H | Schutz, A K | Soragni, A | Amyloid | Amyloid dye | Congo red | Ligand | Prion protein | Protein fibril
