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1wae

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|PDB= 1wae |SIZE=350|CAPTION= <scene name='initialview01'>1wae</scene>, resolution 1.95&Aring;
|PDB= 1wae |SIZE=350|CAPTION= <scene name='initialview01'>1wae</scene>, resolution 1.95&Aring;
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Chain+A'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene> and <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
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|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_1.7.2.1 Transferred entry: 1.7.2.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.99.3 1.7.99.3]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrite_reductase_(NO-forming) Nitrite reductase (NO-forming)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.2.1 1.7.2.1] </span>
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wae OCA], [http://www.ebi.ac.uk/pdbsum/1wae PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1wae RCSB]</span>
}}
}}
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Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15554622 15554622]
Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15554622 15554622]
[[Category: Achromobacter xylosoxidans]]
[[Category: Achromobacter xylosoxidans]]
 +
[[Category: Nitrite reductase (NO-forming)]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Transferred entry: 1 7.2 1]]
 
[[Category: Antonyuk, S V.]]
[[Category: Antonyuk, S V.]]
[[Category: Eady, R R.]]
[[Category: Eady, R R.]]
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[[Category: Sawers, G.]]
[[Category: Sawers, G.]]
[[Category: Strange, R W.]]
[[Category: Strange, R W.]]
-
[[Category: CU]]
 
-
[[Category: ZN]]
 
[[Category: copper protein]]
[[Category: copper protein]]
[[Category: nitrite reductase]]
[[Category: nitrite reductase]]
[[Category: reductase]]
[[Category: reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:54:23 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:33:32 2008''

Revision as of 21:33, 30 March 2008


PDB ID 1wae

Drag the structure with the mouse to rotate
, resolution 1.95Å
Sites:
Ligands: ,
Activity: Nitrite reductase (NO-forming), with EC number 1.7.2.1
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF H129V MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE


Overview

Copper nitrite reductases contain both an electron-transfer type 1 Cu site and a catalytic type 2 Cu site. We have mutated one of the type 2 copper ligating histidines to observe the effect on catalytic turnover. This mutation has created a unique site where Cu is ligated by 2 His Nepsilon2 atoms alone.

About this Structure

1WAE is a Single protein structure of sequence from Achromobacter xylosoxidans. Full crystallographic information is available from OCA.

Reference

Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:15554622

Page seeded by OCA on Mon Mar 31 00:33:32 2008

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