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2mdp
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The bacteriophage T7 encoded inhibitor (gp1.2) of E. coli dGTP triphosphohydrolase== |
| - | + | <StructureSection load='2mdp' size='340' side='right' caption='[[2mdp]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2mdp]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MDP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdp OCA], [http://pdbe.org/2mdp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mdp RCSB], [http://www.ebi.ac.uk/pdbsum/2mdp PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Mueller, G | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/GP12_BPT7 GP12_BPT7]] Plays a role in increasing the intracellular pool of dGTP. Interacts with and inhibits host dGTPase/dgt. The complex made of the host dGTPase and gene 1.2 protein creates a GTP-binding site of high affinity. Subsequent binding of GTP to the enzyme-inhibitor complex inhibits its dissociation.<ref>PMID:2155228</ref> <ref>PMID:3549718</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: London, R E]] | ||
| + | [[Category: Mueller, G A]] | ||
| + | [[Category: Dntpase inhibitor]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 18:36, 12 May 2016
The bacteriophage T7 encoded inhibitor (gp1.2) of E. coli dGTP triphosphohydrolase
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