2mjo

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'''Unreleased structure'''
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==NMR structure of p75 transmembrane domain C257A mutant in DPC micelles==
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<StructureSection load='2mjo' size='340' side='right' caption='[[2mjo]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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The entry 2mjo is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2mjo]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJO FirstGlance]. <br>
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Authors: Nadezhdin, K., Arseniev, A., Goncharuk, S., Mineev, K.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2mic|2mic]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mjo RCSB], [http://www.ebi.ac.uk/pdbsum/2mjo PDBsum]</span></td></tr>
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Description: NMR structure of p75 transmembrane domain C257A mutant in DPC micelles
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Nadezhdin, K]]
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[[http://www.uniprot.org/uniprot/TNR16_RAT TNR16_RAT]] Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
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[[Category: Mineev, K]]
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__TOC__
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[[Category: Goncharuk, S]]
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</StructureSection>
[[Category: Arseniev, A]]
[[Category: Arseniev, A]]
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[[Category: Goncharuk, S]]
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[[Category: Mineev, K]]
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[[Category: Nadezhdin, K]]
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[[Category: C257a mutation]]
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[[Category: Dimer]]
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[[Category: Membrane protein]]
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[[Category: P75]]
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[[Category: Transmembrane]]

Revision as of 16:42, 28 January 2015

NMR structure of p75 transmembrane domain C257A mutant in DPC micelles

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