2mjy
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Solution structure of synthetic Mamba-1 peptide== |
| + | <StructureSection load='2mjy' size='340' side='right' caption='[[2mjy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2mjy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJY FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mjy RCSB], [http://www.ebi.ac.uk/pdbsum/2mjy PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | An efficient one-pot chemical synthesis of snake venom toxin Mambalgin-1 was achieved using an azide-switch strategy combined with hydrazide-based native chemical ligation. Synthetic Mambalgin-1 exhibited a well-defined structure after sequential folding in vitro. NMR spectroscopy revealed a three-finger toxin family structure, and the synthetic toxin inhibited human acid-sensing ion channel 1a. | ||
| - | + | One-pot hydrazide-based native chemical ligation for efficient chemical synthesis and structure determination of toxin Mambalgin-1.,Pan M, He Y, Wen M, Wu F, Sun D, Li S, Zhang L, Li Y, Tian C Chem Commun (Camb). 2014 Jun 4;50(44):5837-9. doi: 10.1039/c4cc00779d. PMID:24619065<ref>PMID:24619065</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: He, Y]] | ||
[[Category: Tian, C]] | [[Category: Tian, C]] | ||
[[Category: Wu, F]] | [[Category: Wu, F]] | ||
| - | [[Category: | + | [[Category: Manba]] |
| + | [[Category: Toxin]] | ||
Revision as of 16:32, 28 January 2015
Solution structure of synthetic Mamba-1 peptide
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