This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2mx1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
==Structure of the E. coli Threonylcarbamoyl-AMP Synthase TSAC==
-
 
+
<StructureSection load='2mx1' size='340' side='right' caption='[[2mx1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-
The entry 2mx1 is ON HOLD until Paper Publication
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2mx1]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MX1 FirstGlance]. <br>
-
Authors: Harris, K.A., Bobay, B.G., Sarachan, K.L., Sims, A.F., Bilbille, Y., Deutsch, C., Iwata-Reuyl, D., Agris, P.F.
+
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-threonylcarbamoyladenylate_synthase L-threonylcarbamoyladenylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.87 2.7.7.87] </span></td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mx1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mx1 RCSB], [http://www.ebi.ac.uk/pdbsum/2mx1 PDBsum]</span></td></tr>
-
Description: Structure of the E. coli threonylcarbamoyl-AMP synthase YrdC
+
</table>
-
[[Category: Unreleased Structures]]
+
== Function ==
-
[[Category: Sims, A.F]]
+
[[http://www.uniprot.org/uniprot/TSAC_ECOLI TSAC_ECOLI]] Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, bicarbonate/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of pyrophosphate. Is also able to catalyze the reverse reaction in vitro, i.e. the formation of ATP from TC-AMP and PPi. Shows higher affinity for the full-length tRNA(Thr) lacking only the t(6)A37 modification than for its fully modified counterpart. Could also be required for the maturation of 16S rRNA. Binds to double-stranded RNA but does not interact tightly with either of the ribosomal subunits, or the 70S particles.[HAMAP-Rule:MF_01852]<ref>PMID:15716138</ref> <ref>PMID:19287007</ref> <ref>PMID:21285948</ref> <ref>PMID:22378793</ref> <ref>PMID:23072323</ref>
-
[[Category: Bobay, B.G]]
+
== References ==
-
[[Category: Agris, P.F]]
+
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: L-threonylcarbamoyladenylate synthase]]
 +
[[Category: Agris, P F]]
 +
[[Category: Bilbille, Y]]
 +
[[Category: Bobay, B G]]
[[Category: Deutsch, C]]
[[Category: Deutsch, C]]
-
[[Category: Sarachan, K.L]]
+
[[Category: Harris, K A]]
[[Category: Iwata-Reuyl, D]]
[[Category: Iwata-Reuyl, D]]
-
[[Category: Harris, K.A]]
+
[[Category: Sarachan, K L]]
-
[[Category: Bilbille, Y]]
+
[[Category: Sims, A F]]
 +
[[Category: Transferase]]

Revision as of 15:19, 17 June 2015

Structure of the E. coli Threonylcarbamoyl-AMP Synthase TSAC

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2mx1"
Personal tools