3wsa
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole== |
| - | + | <StructureSection load='3wsa' size='340' side='right' caption='[[3wsa]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3wsa]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WSA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wsb|3wsb]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wsa RCSB], [http://www.ebi.ac.uk/pdbsum/3wsa PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Huang, C | + | </StructureSection> |
| + | [[Category: Squalene synthase]] | ||
| + | [[Category: Guo, R T]] | ||
| + | [[Category: Huang, C H]] | ||
[[Category: Li, Q]] | [[Category: Li, Q]] | ||
| - | [[Category: | + | [[Category: Oldfield, E]] |
| + | [[Category: Shang, N]] | ||
| + | [[Category: Drug discovery]] | ||
| + | [[Category: Human squalene synthase]] | ||
| + | [[Category: Isoprenoid]] | ||
| + | [[Category: Sq-109]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 13:17, 1 April 2015
The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole
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