4ir0
From Proteopedia
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==Crystal Structure of Metallothiol Transferase FosB 2 from Bacillus anthracis str. Ames== | ==Crystal Structure of Metallothiol Transferase FosB 2 from Bacillus anthracis str. Ames== | ||
<StructureSection load='4ir0' size='340' side='right' caption='[[4ir0]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4ir0' size='340' side='right' caption='[[4ir0]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ir0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4ir0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_ames) Bacillus anthracis (strain ames)]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3uh9 3uh9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IR0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IR0 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAS3818, BA_4109, fosB-2, fosB2, GBAA_4109 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAS3818, BA_4109, fosB-2, fosB2, GBAA_4109 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ir0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ir0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ir0 RCSB], [http://www.ebi.ac.uk/pdbsum/4ir0 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ir0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ir0 OCA], [http://pdbe.org/4ir0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ir0 RCSB], [http://www.ebi.ac.uk/pdbsum/4ir0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ir0 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/FOSB2_BACAN FOSB2_BACAN]] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512] | [[http://www.uniprot.org/uniprot/FOSB2_BACAN FOSB2_BACAN]] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512] | ||
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| + | ==See Also== | ||
| + | *[[Metallothiol transferase FosB|Metallothiol transferase FosB]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Bacillus anthracis str. ames]] | ||
[[Category: Anderson, W F]] | [[Category: Anderson, W F]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
Revision as of 10:49, 4 August 2016
Crystal Structure of Metallothiol Transferase FosB 2 from Bacillus anthracis str. Ames
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