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1a0m

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<StructureSection load='1a0m' size='340' side='right' caption='[[1a0m]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
<StructureSection load='1a0m' size='340' side='right' caption='[[1a0m]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1a0m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Conus_episcopatus Conus episcopatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A0M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1a0m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bishop's_cone Bishop's cone]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A0M FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a0m RCSB], [http://www.ebi.ac.uk/pdbsum/1a0m PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0m OCA], [http://pdbe.org/1a0m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a0m RCSB], [http://www.ebi.ac.uk/pdbsum/1a0m PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CXA1_CONEP CXA1_CONEP]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This peptide blocks mammalian nicotinic acetylcholine receptors composed of alpha-3/beta-2 and alpha-3/beta-4 subunits.
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[[http://www.uniprot.org/uniprot/CA1_CONEP CA1_CONEP]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This peptide blocks mammalian nicotinic acetylcholine receptors composed of alpha-3/beta-2 and alpha-3/beta-4 subunits.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1a0m" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Conus episcopatus]]
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[[Category: Bishop's cone]]
[[Category: Alewood, P F]]
[[Category: Alewood, P F]]
[[Category: Blessing, R H]]
[[Category: Blessing, R H]]

Revision as of 16:07, 9 September 2015

1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI

1a0m, resolution 1.10Å

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