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4cvh
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of human isoprenoid synthase domain-containing protein== |
| - | + | <StructureSection load='4cvh' size='340' side='right' caption='[[4cvh]], [[Resolution|resolution]] 2.39Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4cvh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cvh RCSB], [http://www.ebi.ac.uk/pdbsum/4cvh PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Disease == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/ISPD_HUMAN ISPD_HUMAN]] Autosomal recessive limb-girdle muscular dystrophy due to ISPD deficiency;Congenital muscular dystrophy without intellectual disability;Walker-Warburg syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/ISPD_HUMAN ISPD_HUMAN]] Required for protein O-linked mannosylation. Probably acts as a nucleotidyltransferase involved in synthesis of a nucleotide sugar. Required for dystroglycan O-mannosylation.<ref>PMID:22522420</ref> <ref>PMID:22522421</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C]] | ||
| + | [[Category: Bountra, C]] | ||
[[Category: Burgess-Brown, N]] | [[Category: Burgess-Brown, N]] | ||
| - | [[Category: | + | [[Category: Delft, F von]] |
| + | [[Category: Edwards, A]] | ||
| + | [[Category: Froese, D S]] | ||
| + | [[Category: Goubin, S]] | ||
[[Category: Kiyani, W]] | [[Category: Kiyani, W]] | ||
[[Category: Kopec, J]] | [[Category: Kopec, J]] | ||
| - | [[Category: | + | [[Category: Krojer, T]] |
| - | [[Category: | + | [[Category: Lefeber, D J]] |
[[Category: Newman, J]] | [[Category: Newman, J]] | ||
| - | [[Category: Froese, D.S]] | ||
| - | [[Category: Edwards, A]] | ||
[[Category: Strain-Damerell, C]] | [[Category: Strain-Damerell, C]] | ||
| - | [[Category: Krojer, T]] | ||
| - | [[Category: Bountra, C]] | ||
[[Category: Vollmar, M]] | [[Category: Vollmar, M]] | ||
| + | [[Category: Yue, W W]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 15:54, 7 February 2015
Crystal structure of human isoprenoid synthase domain-containing protein
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Categories: Arrowsmith, C | Bountra, C | Burgess-Brown, N | Delft, F von | Edwards, A | Froese, D S | Goubin, S | Kiyani, W | Kopec, J | Krojer, T | Lefeber, D J | Newman, J | Strain-Damerell, C | Vollmar, M | Yue, W W | Transferase
