4d6w
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal Structure of the low pH conformation of Chandipura Virus glycoprotein G ectodomain== |
| - | + | <StructureSection load='4d6w' size='340' side='right' caption='[[4d6w]], [[Resolution|resolution]] 3.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4d6w]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D6W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d6w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d6w RCSB], [http://www.ebi.ac.uk/pdbsum/4d6w PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/GLYCO_CHAV GLYCO_CHAV]] Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane (By similarity). |
| - | [[ | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Albertini, A]] | [[Category: Albertini, A]] | ||
| - | [[Category: Gaudin, Y]] | ||
[[Category: Baquero, E]] | [[Category: Baquero, E]] | ||
| + | [[Category: Bressanelli, S]] | ||
| + | [[Category: Gaudin, Y]] | ||
| + | [[Category: Raux, H]] | ||
| + | [[Category: Membrane fusion]] | ||
| + | [[Category: Rhabdovirus]] | ||
| + | [[Category: Viral entry]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 11:31, 4 March 2015
Crystal Structure of the low pH conformation of Chandipura Virus glycoprotein G ectodomain
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