This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4n1p
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Structure of Cyclophilin A in complex with Picolinamide.== |
| - | + | <StructureSection load='4n1p' size='340' side='right' caption='[[4n1p]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4n1p]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=WM1:PYRIDINE-2-CARBOXAMIDE'>WM1</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n1m|4n1m]], [[4n1n|4n1n]], [[4n1o|4n1o]], [[4n1q|4n1q]], [[4n1r|4n1r]], [[4n1s|4n1s]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n1p RCSB], [http://www.ebi.ac.uk/pdbsum/4n1p PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Peptidylprolyl isomerase]] | ||
[[Category: Dornan, J]] | [[Category: Dornan, J]] | ||
| - | [[Category: Walkinshaw, M | + | [[Category: Mcnae, I W]] |
| + | [[Category: Walkinshaw, M D]] | ||
| + | [[Category: Beta barrel]] | ||
| + | [[Category: Cytosolic]] | ||
| + | [[Category: Isomerase]] | ||
| + | [[Category: Ligand complex]] | ||
| + | [[Category: Prolyl cis/trans isomerase]] | ||
Revision as of 14:44, 12 August 2015
Structure of Cyclophilin A in complex with Picolinamide.
| |||||||||||
