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1ont
From Proteopedia
(Difference between revisions)
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<StructureSection load='1ont' size='340' side='right' caption='[[1ont]], [[NMR_Ensembles_of_Models | 17 NMR models]]' scene=''> | <StructureSection load='1ont' size='340' side='right' caption='[[1ont]], [[NMR_Ensembles_of_Models | 17 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1ont]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1ont]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Contu Contu]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONT FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ont FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ont OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ont RCSB], [http://www.ebi.ac.uk/pdbsum/1ont PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ont FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ont OCA], [http://pdbe.org/1ont PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ont RCSB], [http://www.ebi.ac.uk/pdbsum/1ont PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/CKT_CONTU CKT_CONTU]] Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors. This toxin inhibits both NR2A and NR2B subunits of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons. Induces sleep-like symptoms in young mice and hyperactivity in older mice.<ref>PMID:2165278</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 1ont" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Contu]] |
[[Category: Alewood, P F]] | [[Category: Alewood, P F]] | ||
[[Category: Craik, D J]] | [[Category: Craik, D J]] | ||
Revision as of 00:34, 10 September 2015
NMDA RECEPTOR ANTAGONIST, CONANTOKIN-T, NMR, 17 STRUCTURES
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