4onv

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'''Unreleased structure'''
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==Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate==
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<StructureSection load='4onv' size='340' side='right' caption='[[4onv]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
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The entry 4onv is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4onv]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ONV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ONV FirstGlance]. <br>
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Authors: Manoj Kumar, P., Bhaskar, V., Manicka, S., Krishnaswamy, S.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KDG:2-KETO-3-DEOXYGLUCONATE'>KDG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4onv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4onv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4onv RCSB], [http://www.ebi.ac.uk/pdbsum/4onv PDBsum]</span></td></tr>
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Description: Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Manoj Kumar, P]]
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[[http://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI]] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.
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[[Category: Manicka, S]]
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__TOC__
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</StructureSection>
[[Category: Bhaskar, V]]
[[Category: Bhaskar, V]]
[[Category: Krishnaswamy, S]]
[[Category: Krishnaswamy, S]]
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[[Category: Kumar, P Manoj]]
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[[Category: Manicka, S]]
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[[Category: Aldolase class i]]
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[[Category: Lyase]]
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[[Category: Nal superfamily]]
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[[Category: Tim barrel]]

Revision as of 13:32, 14 January 2015

Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate

4onv, resolution 2.57Å

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