4opn

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'''Unreleased structure'''
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==Crystal structure of mouse glyoxalase I complexed with mAH==
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<StructureSection load='4opn' size='340' side='right' caption='[[4opn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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The entry 4opn is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4opn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OPN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OPN FirstGlance]. <br>
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Authors: Zhai, J., Zhang, L., Yuan, M., Zhang, H.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZBF:L-GAMMA-GLUTAMYL-N-(3-ETHYNYLPHENYL)-N-HYDROXY-L-GLUTAMINYLGLYCINE'>ZBF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lactoylglutathione_lyase Lactoylglutathione lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.5 4.4.1.5] </span></td></tr>
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Description: Crystal structure of mouse glyoxalase I complexed with mAH
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4opn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4opn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4opn RCSB], [http://www.ebi.ac.uk/pdbsum/4opn PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Zhang, H]]
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== Function ==
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[[Category: Zhang, L]]
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[[http://www.uniprot.org/uniprot/LGUL_MOUSE LGUL_MOUSE]] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Lactoylglutathione lyase]]
[[Category: Yuan, M]]
[[Category: Yuan, M]]
[[Category: Zhai, J]]
[[Category: Zhai, J]]
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[[Category: Zhang, H]]
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[[Category: Zhang, L]]
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[[Category: Lyase-lyase inhibitor complex]]
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[[Category: Lyase/lyase inhibitor]]

Revision as of 11:57, 12 February 2015

Crystal structure of mouse glyoxalase I complexed with mAH

4opn, resolution 2.10Å

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