This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4ow8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
==Crystal structure of kinase domain of PknA from Mtb==
-
 
+
<StructureSection load='4ow8' size='340' side='right' caption='[[4ow8]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
-
The entry 4ow8 is ON HOLD until Paper Publication
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4ow8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OW8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OW8 FirstGlance]. <br>
-
Authors: Ravala, S.K., Singh, S., Yadav, G.S., Karthikeyan, S., Chakraborti, P.K.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
 
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-
Description: Crystal structure of kinase domain of PknA from Mtb
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ow8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ow8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ow8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ow8 PDBsum]</span></td></tr>
-
[[Category: Unreleased Structures]]
+
</table>
-
[[Category: Chakraborti, P.K]]
+
== Function ==
-
[[Category: Yadav, G.S]]
+
[[http://www.uniprot.org/uniprot/PKNA_MYCTU PKNA_MYCTU]] Key component of a signal transduction pathway that regulates cell growth and cell division via phosphorylation of target proteins such as FtsZ, Wag31, GlmU, FhaB, PstP, EmbR and Rv1422. Shows a strong preference for Thr versus Ser as the phosphoacceptor.<ref>PMID:15985609</ref> <ref>PMID:16817899</ref> <ref>PMID:19121323</ref> <ref>PMID:20066037</ref> <ref>PMID:21190553</ref> <ref>PMID:21423706</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Non-specific serine/threonine protein kinase]]
 +
[[Category: Chakraborti, P K]]
[[Category: Karthikeyan, S]]
[[Category: Karthikeyan, S]]
 +
[[Category: Ravala, S K]]
[[Category: Singh, S]]
[[Category: Singh, S]]
-
[[Category: Ravala, S.K]]
+
[[Category: Yadav, G S]]
 +
[[Category: Drug target]]
 +
[[Category: Kinase]]
 +
[[Category: Mtb]]
 +
[[Category: Pkna]]

Revision as of 15:56, 7 February 2015

Crystal structure of kinase domain of PknA from Mtb

4ow8, resolution 2.03Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ow8"
Personal tools