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4p5b

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'''Unreleased structure'''
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==Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br dUMP==
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<StructureSection load='4p5b' size='340' side='right' caption='[[4p5b]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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The entry 4p5b is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4p5b]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P5B FirstGlance]. <br>
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Authors: Li, Y., Chen, W., Li, J., Xia, Z., Deng, Z., Zhou, J.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p5a|4p5a]], [[4p5c|4p5c]]</td></tr>
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Description: Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br dUMP
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase_(FAD) Thymidylate synthase (FAD)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.148 2.1.1.148] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p5b OCA], [http://pdbe.org/4p5b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p5b RCSB], [http://www.ebi.ac.uk/pdbsum/4p5b PDBsum]</span></td></tr>
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[[Category: Xia, Z]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/C1IC19_STRCI C1IC19_STRCI]] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.[HAMAP-Rule:MF_01408]
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__TOC__
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</StructureSection>
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[[Category: Chen, W]]
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[[Category: Deng, Z]]
[[Category: Li, J]]
[[Category: Li, J]]
[[Category: Li, Y]]
[[Category: Li, Y]]
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[[Category: Chen, W]]
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[[Category: Xia, Z]]
[[Category: Zhou, J]]
[[Category: Zhou, J]]
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[[Category: Deng, Z]]
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[[Category: Tetramer]]
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[[Category: Thyx homolog]]
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[[Category: Transferase]]
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[[Category: Ump/dump methylase]]

Revision as of 13:45, 9 December 2015

Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br dUMP

4p5b, resolution 2.27Å

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