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4px2
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Human GKRP bound to AMG2882 and Sorbitol-6-Phosphate== |
| - | + | <StructureSection load='4px2' size='340' side='right' caption='[[4px2]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4px2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PX2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2WY:N-[(R)-1-BENZOFURAN-2-YL(PHENYL)METHYL]-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE-7-SULFONAMIDE'>2WY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4px3|4px3]], [[4px5|4px5]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4px2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4px2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4px2 RCSB], [http://www.ebi.ac.uk/pdbsum/4px2 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN]] Inhibits glucokinase by forming an inactive complex with this enzyme. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Chmait, S]] | [[Category: Chmait, S]] | ||
| - | [[Category: Jordan, S | + | [[Category: Jordan, S R]] |
| + | [[Category: Glucokinase]] | ||
| + | [[Category: Regulatory protein - binds to and inhibits glucokinase]] | ||
| + | [[Category: Sis domain containing protein]] | ||
| + | [[Category: Sugar binding protein-inhibitor complex]] | ||
Revision as of 12:22, 13 May 2015
Human GKRP bound to AMG2882 and Sorbitol-6-Phosphate
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