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4l5m

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==Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH6.5==
==Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH6.5==
<StructureSection load='4l5m' size='340' side='right' caption='[[4l5m]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4l5m' size='340' side='right' caption='[[4l5m]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4l5m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L5M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4l5m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L5M FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HRC:N-(4-HYDROXY-2,6-DIMETHYLPHENYL)BENZENESULFONAMIDE'>HRC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HRC:N-(4-HYDROXY-2,6-DIMETHYLPHENYL)BENZENESULFONAMIDE'>HRC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jmi|4jmi]], [[4jwl|4jwl]], [[4jhx|4jhx]], [[4jmo|4jmo]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jmi|4jmi]], [[4jwl|4jwl]], [[4jhx|4jhx]], [[4jmo|4jmo]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYTH2, ARNO, PSCD2, PSCD2L ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYTH2, ARNO, PSCD2, PSCD2L ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l5m RCSB], [http://www.ebi.ac.uk/pdbsum/4l5m PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5m OCA], [http://pdbe.org/4l5m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4l5m RCSB], [http://www.ebi.ac.uk/pdbsum/4l5m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4l5m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4l5m" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Hoh, F]]
[[Category: Hoh, F]]
[[Category: Rouhana, J]]
[[Category: Rouhana, J]]
[[Category: Sec-7domain]]
[[Category: Sec-7domain]]
[[Category: Signaling protein-inhibitor complex]]
[[Category: Signaling protein-inhibitor complex]]

Revision as of 14:07, 4 August 2016

Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH6.5

4l5m, resolution 1.80Å

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