4qo3
From Proteopedia
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| - | ''' | + | ==Crystal structure of C16S/N18S/K12V/C117V/P134V mutant of human acidic fibroblast growth factor== |
| - | + | <StructureSection load='4qo3' size='340' side='right' caption='[[4qo3]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4qo3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QO3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2afg|2afg]], [[1jqz|1jqz]], [[1rg8|1rg8]], [[4q91|4q91]], [[4q9g|4q9g]], [[4q9p|4q9p]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qo3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qo3 RCSB], [http://www.ebi.ac.uk/pdbsum/4qo3 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Blaber, M]] | [[Category: Blaber, M]] | ||
[[Category: Xia, X]] | [[Category: Xia, X]] | ||
| + | [[Category: Beta-trefoil]] | ||
| + | [[Category: Fgfr binding]] | ||
| + | [[Category: Growth factor]] | ||
| + | [[Category: Heparin binding]] | ||
| + | [[Category: Protein binding]] | ||
Revision as of 12:58, 6 May 2015
Crystal structure of C16S/N18S/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
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