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4re5

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'''Unreleased structure'''
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==Acylaminoacyl peptidase complexed with a chloromethylketone inhibitor==
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<StructureSection load='4re5' size='340' side='right' caption='[[4re5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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The entry 4re5 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4re5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RE5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RE5 FirstGlance]. <br>
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Authors: Menyhard, D.K., Orgovan, Z., Szeltner, Z., Szamosi, I., Harmat, V.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=Y3A:N-[(BENZYLOXY)CARBONYL]GLYCYL-N-[(2S,3R)-4-CHLORO-3-HYDROXY-1-PHENYLBUTAN-2-YL]GLYCINAMIDE'>Y3A</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4re6|4re6]]</td></tr>
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Description: Acylaminoacyl peptidase complexed with a chloromethylketone inhibitor
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acylaminoacyl-peptidase Acylaminoacyl-peptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.1 3.4.19.1] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4re5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4re5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4re5 RCSB], [http://www.ebi.ac.uk/pdbsum/4re5 PDBsum]</span></td></tr>
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[[Category: Orgovan, Z]]
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</table>
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[[Category: Menyhard, D.K]]
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== Function ==
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[[http://www.uniprot.org/uniprot/APEH_AERPE APEH_AERPE]] This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus.
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__TOC__
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</StructureSection>
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[[Category: Acylaminoacyl-peptidase]]
[[Category: Harmat, V]]
[[Category: Harmat, V]]
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[[Category: Menyhard, D K]]
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[[Category: Orgovan, Z]]
[[Category: Szamosi, I]]
[[Category: Szamosi, I]]
[[Category: Szeltner, Z]]
[[Category: Szeltner, Z]]
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[[Category: Alpha-beta-hydrolase fold]]
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[[Category: Beta-propeller]]
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[[Category: Chloromethyl-ketone inhibitor]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 16:46, 28 January 2015

Acylaminoacyl peptidase complexed with a chloromethylketone inhibitor

4re5, resolution 1.90Å

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