4rm8

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'''Unreleased structure'''
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==Crystal structure of human ezrin in space group P21==
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<StructureSection load='4rm8' size='340' side='right' caption='[[4rm8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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The entry 4rm8 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4rm8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RM8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RM8 FirstGlance]. <br>
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Authors: Phang, J.M., Harrop, S.J., Davies, R., Duff, A.P., Wilk, K.E., Curmi, P.M.G.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rm9|4rm9]], [[4rma|4rma]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rm8 OCA], [http://pdbe.org/4rm8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rm8 RCSB], [http://www.ebi.ac.uk/pdbsum/4rm8 PDBsum]</span></td></tr>
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Description: Crystal structure of human ezrin in space group P21
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Phang, J.M]]
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[[http://www.uniprot.org/uniprot/EZRI_HUMAN EZRI_HUMAN]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.<ref>PMID:17881735</ref> <ref>PMID:18270268</ref> <ref>PMID:19111582</ref>
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[[Category: Duff, A.P]]
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== References ==
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[[Category: Curmi, P.M.G]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Curmi, P M.G]]
[[Category: Davies, R]]
[[Category: Davies, R]]
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[[Category: Wilk, K.E]]
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[[Category: Duff, A P]]
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[[Category: Harrop, S.J]]
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[[Category: Harrop, S J]]
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[[Category: Phang, J M]]
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[[Category: Wilk, K E]]
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[[Category: Actin binding]]
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[[Category: C-ermad domain]]
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[[Category: Ferm domain]]
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[[Category: Membrane cytoskeleton linker]]
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[[Category: Peptide binding protein]]

Revision as of 13:45, 9 December 2015

Crystal structure of human ezrin in space group P21

4rm8, resolution 1.90Å

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