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4rv3
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of a pentafluoro-Phe incorporated Phosphatidylinositol-specific phospholipase C (H258X)from Staphylococcus aureus== |
| - | + | <StructureSection load='4rv3' size='340' side='right' caption='[[4rv3]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RV3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PF5:2,3,4,5,6-PENTAFLUORO-L-PHENYLALANINE'>PF5</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v16|3v16]]</td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol_diacylglycerol-lyase Phosphatidylinositol diacylglycerol-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.13 4.6.1.13] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rv3 RCSB], [http://www.ebi.ac.uk/pdbsum/4rv3 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PLC_STAAE PLC_STAAE]] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Phosphatidylinositol diacylglycerol-lyase]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Eyles, S J]] | ||
| + | [[Category: Gao, J]] | ||
[[Category: Gershenson, A]] | [[Category: Gershenson, A]] | ||
| - | [[Category: Roberts, M.F]] | ||
| - | [[Category: Eyles, S.J]] | ||
[[Category: He, T]] | [[Category: He, T]] | ||
| - | [[Category: | + | [[Category: Roberts, M F]] |
| + | [[Category: Cation-pi]] | ||
| + | [[Category: Encoded unnatural amino acid phospholipase]] | ||
| + | [[Category: Lyase]] | ||
| + | [[Category: Tim barrel]] | ||
Revision as of 12:19, 1 July 2015
Crystal structure of a pentafluoro-Phe incorporated Phosphatidylinositol-specific phospholipase C (H258X)from Staphylococcus aureus
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