1yfg

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|PDB= 1yfg |SIZE=350|CAPTION= <scene name='initialview01'>1yfg</scene>, resolution 3.000&Aring;
|PDB= 1yfg |SIZE=350|CAPTION= <scene name='initialview01'>1yfg</scene>, resolution 3.000&Aring;
|SITE=
|SITE=
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|LIGAND=
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|LIGAND= <scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5&#39;-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=1MG:1N-METHYLGUANOSINE-5&#39;-MONOPHOSPHATE'>1MG</scene>, <scene name='pdbligand=2MG:2N-METHYLGUANOSINE-5&#39;-MONOPHOSPHATE'>2MG</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5&#39;-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=7MG:7N-METHYL-8-HYDROGUANOSINE-5&#39;-MONOPHOSPHATE'>7MG</scene>, <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5&#39;-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=M2G:N2-DIMETHYLGUANOSINE-5&#39;-MONOPHOSPHATE'>M2G</scene>, <scene name='pdbligand=RIA:2&#39;-O-[(5&#39;-PHOSPHO)RIBOSYL]ADENOSINE-5&#39;-MONOPHOSPHATE'>RIA</scene>, <scene name='pdbligand=T6A:N-[N-(9-B-D-RIBOFURANOSYLPURIN-6-YL)CARBAMOYL]THREONINE-5&#39;-MONOPHOSPHATE'>T6A</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yfg OCA], [http://www.ebi.ac.uk/pdbsum/1yfg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1yfg RCSB]</span>
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[[Category: transfer ribonucleic acid]]
[[Category: transfer ribonucleic acid]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:22:11 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:05:35 2008''

Revision as of 22:05, 30 March 2008


PDB ID 1yfg

Drag the structure with the mouse to rotate
, resolution 3.000Å
Ligands: , , , , , , , , , , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



YEAST INITIATOR TRNA


Overview

A significantly improved molecular model of yeast initiator tRNA (ytRNA(iMet) has been prepared that gives insight into the structural basis of eukaryotic initiator tRNA's unique function. This study was made possible by X-ray data collected at synchrotron radiation sources with the newly developed technologies of 'imaging plates' and 'storage phosphors'. These data extend beyond the resolution limit of 4.0 A reported previously to a current limit of 3.0 A and are considerably more accurate. Refinement of the model against the new data (R factor = 21.5%) clearly reveals a novel modification and a set of tertiary interactions involving sequence features characteristic of eukaryotic initiator tRNAs. We hypothesize these to be the structural elements responsible for part of the special function of yeast tRNA(iMET).

About this Structure

1YFG is a Protein complex structure of sequences from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YFG with [Transfer RNA]. Full crystallographic information is available from OCA.

Reference

The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination., Basavappa R, Sigler PB, EMBO J. 1991 Oct;10(10):3105-11. PMID:1915284

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