4tuv

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'''Unreleased structure'''
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==X-ray crystal structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-chlorophenyl)imidazole==
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<StructureSection load='4tuv' size='340' side='right' caption='[[4tuv]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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The entry 4tuv is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4tuv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TUV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TUV FirstGlance]. <br>
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Authors: Madrona, Y.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPZ:4-(4-CHLOROPHENYL)IMIDAZOLE'>CPZ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tt5|4tt5]]</td></tr>
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Description: X-ray crystal structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-chlorophenyl)imidazole
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tuv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tuv RCSB], [http://www.ebi.ac.uk/pdbsum/4tuv PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CP119_SULAC CP119_SULAC]] The endogenous substrate is not known. In vitro, catalyzes the H(2)O(2)-dependent epoxidation of styrene, cis-beta-methylstyrene, and cis-stilbene with retention of stereochemistry. Is able to use cumene hydroperoxide (CHP) or tert-butyl hydroperoxide (TBHP) instead of H(2)O(2) as the electron acceptor. Can also hydroxylate fatty acids such as lauric acid.<ref>PMID:10799487</ref> <ref>PMID:12010041</ref> <ref>PMID:18157853</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Madrona, Y]]
[[Category: Madrona, Y]]
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[[Category: Oxidoreductase]]

Revision as of 13:08, 18 February 2015

X-ray crystal structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-chlorophenyl)imidazole

4tuv, resolution 2.50Å

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