3q2h

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==Adamts1 in complex with N-hydroxyformamide inhibitors of ADAM-TS4==
==Adamts1 in complex with N-hydroxyformamide inhibitors of ADAM-TS4==
<StructureSection load='3q2h' size='340' side='right' caption='[[3q2h]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
<StructureSection load='3q2h' size='340' side='right' caption='[[3q2h]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3q2h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q2H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3q2h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q2H FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=QHF:N-[(2S,4S)-1-({4-[2-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)ETHYL]PIPERIDIN-1-YL}SULFONYL)-4-(5-FLUOROPYRIMIDIN-2-YL)-2-METHYLPENTAN-2-YL]-N-HYDROXYFORMAMIDE'>QHF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=QHF:N-[(2S,4S)-1-({4-[2-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)ETHYL]PIPERIDIN-1-YL}SULFONYL)-4-(5-FLUOROPYRIMIDIN-2-YL)-2-METHYLPENTAN-2-YL]-N-HYDROXYFORMAMIDE'>QHF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q2g|3q2g]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q2g|3q2g]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAMTS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAMTS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2h RCSB], [http://www.ebi.ac.uk/pdbsum/3q2h PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2h OCA], [http://pdbe.org/3q2h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q2h RCSB], [http://www.ebi.ac.uk/pdbsum/3q2h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3q2h" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Gerhardt, S]]
[[Category: Gerhardt, S]]
[[Category: Hargreaves, D]]
[[Category: Hargreaves, D]]

Revision as of 18:37, 4 August 2016

Adamts1 in complex with N-hydroxyformamide inhibitors of ADAM-TS4

3q2h, resolution 2.33Å

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