4uct
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Fragment bound to H.influenza NAD dependent DNA ligase== |
| - | + | <StructureSection load='4uct' size='340' side='right' caption='[[4uct]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4uct]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UCT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5U1:2-AMINO-6-METHYL-5-(PROPAN-2-YLOXY)-3H-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-8-IUM'>5U1</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uco|4uco]], [[4ucr|4ucr]], [[4ucs|4ucs]], [[4ucu|4ucu]], [[4ucv|4ucv]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uct OCA], [http://pdbe.org/4uct PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uct RCSB], [http://www.ebi.ac.uk/pdbsum/4uct PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN]] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Boriack-Sjodin, P A]] | ||
| + | [[Category: Brassington, C]] | ||
| + | [[Category: Carcanague, D]] | ||
[[Category: Embrey, K]] | [[Category: Embrey, K]] | ||
| - | [[Category: | + | [[Category: Eyermann, C J]] |
| - | [[Category: | + | [[Category: Giacobbe, R A]] |
| - | [[Category: | + | [[Category: Gingipali, L]] |
[[Category: Gowravaram, M]] | [[Category: Gowravaram, M]] | ||
[[Category: Hale, M]] | [[Category: Hale, M]] | ||
| - | [[Category: | + | [[Category: Harang, J]] |
[[Category: Howard, T]] | [[Category: Howard, T]] | ||
| - | [[Category: | + | [[Category: Ioannidis, G]] |
| - | + | ||
| - | + | ||
[[Category: Jahic, H]] | [[Category: Jahic, H]] | ||
| - | [[Category: Murphy-Benenato, K.E]] | ||
[[Category: Kutschke, A]] | [[Category: Kutschke, A]] | ||
| - | [[Category: | + | [[Category: Laganas, V A]] |
| - | [[Category: | + | [[Category: Loch, J]] |
| - | [[Category: | + | [[Category: Miller, M D]] |
| + | [[Category: Murphy-Benenato, K E]] | ||
[[Category: Oguto, H]] | [[Category: Oguto, H]] | ||
| - | [[Category: | + | [[Category: Otterbein, L]] |
| - | [[Category: | + | [[Category: Patel, S J]] |
| - | [[Category: | + | [[Category: Shapiro, A B]] |
| + | [[Category: Ligase]] | ||
Revision as of 04:02, 16 October 2015
Fragment bound to H.influenza NAD dependent DNA ligase
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Categories: Boriack-Sjodin, P A | Brassington, C | Carcanague, D | Embrey, K | Eyermann, C J | Giacobbe, R A | Gingipali, L | Gowravaram, M | Hale, M | Harang, J | Howard, T | Ioannidis, G | Jahic, H | Kutschke, A | Laganas, V A | Loch, J | Miller, M D | Murphy-Benenato, K E | Oguto, H | Otterbein, L | Patel, S J | Shapiro, A B | Ligase
