1yq5
From Proteopedia
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|PDB= 1yq5 |SIZE=350|CAPTION= <scene name='initialview01'>1yq5</scene>, resolution 2.0Å | |PDB= 1yq5 |SIZE=350|CAPTION= <scene name='initialview01'>1yq5</scene>, resolution 2.0Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1yq6|1YQ6]], [[1yq8|1YQ8]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yq5 OCA], [http://www.ebi.ac.uk/pdbsum/1yq5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1yq5 RCSB]</span> | ||
}} | }} | ||
| Line 30: | Line 33: | ||
[[Category: beta-spiral]] | [[Category: beta-spiral]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:17:41 2008'' |
Revision as of 22:17, 30 March 2008
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| , resolution 2.0Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Related: | 1YQ6, 1YQ8
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
PRD1 vertex protein P5
Overview
Comparisons of bacteriophage PRD1 and adenovirus protein structures and virion architectures have been instrumental in unraveling an evolutionary relationship and have led to a proposal of a phylogeny-based virus classification. The structure of the PRD1 spike protein P5 provides further insight into the evolution of viral proteins. The crystallized P5 fragment comprises two structural domains: a globular knob and a fibrous shaft. The head folds into a ten-stranded jelly roll beta barrel, which is structurally related to the tumor necrosis factor (TNF) and the PRD1 coat protein domains. The shaft domain is a structural counterpart to the adenovirus spike shaft. The structural relationships between PRD1, TNF, and adenovirus proteins suggest that the vertex proteins may have originated from an ancestral TNF-like jelly roll coat protein via a combination of gene duplication and deletion.
About this Structure
1YQ5 is a Single protein structure of sequence from Enterobacteria phage prd1. Full crystallographic information is available from OCA.
Reference
The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture., Merckel MC, Huiskonen JT, Bamford DH, Goldman A, Tuma R, Mol Cell. 2005 Apr 15;18(2):161-70. PMID:15837420
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