4unl
From Proteopedia
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| - | ''' | + | ==Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human== |
| - | + | <StructureSection load='4unl' size='340' side='right' caption='[[4unl]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4unl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UNL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UNL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4unk|4unk]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4unl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4unl RCSB], [http://www.ebi.ac.uk/pdbsum/4unl PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Disease == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[http://omim.org/entry/190450 190450]]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Triose-phosphate isomerase]] | ||
[[Category: Castillo-Villanueva, A]] | [[Category: Castillo-Villanueva, A]] | ||
| - | [[Category: | + | [[Category: DeLaMora-DeLaMora, I]] |
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[[Category: Enriquez-Flores, S]] | [[Category: Enriquez-Flores, S]] | ||
| - | [[Category: Torres- | + | [[Category: Garcia-Torres, I]] |
| + | [[Category: Gomez-Manzo, S]] | ||
| + | [[Category: Lopez-Velazquez, G]] | ||
[[Category: Marcial-Quino, J]] | [[Category: Marcial-Quino, J]] | ||
| + | [[Category: Mendez, S T]] | ||
| + | [[Category: Oria-Hernandez, J]] | ||
| + | [[Category: Reyes-Vivas, H]] | ||
[[Category: Torres-Arroyo, A]] | [[Category: Torres-Arroyo, A]] | ||
| + | [[Category: Torres-Larios, A]] | ||
| + | [[Category: Deamidation]] | ||
| + | [[Category: Isomerase]] | ||
Revision as of 16:00, 7 February 2015
Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human
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