4unp
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Mtb TMK in complex with compound 34== |
| - | + | <StructureSection load='4unp' size='340' side='right' caption='[[4unp]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4unp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UNP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TXW:5-METHYL-7-PROPYL-1,6-NAPHTHYRIDIN-2(1H)-ONE'>TXW</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4unn|4unn]], [[4unq|4unq]], [[4unr|4unr]], [[4uns|4uns]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4unp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4unp RCSB], [http://www.ebi.ac.uk/pdbsum/4unp PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KTHY_MYCTO KTHY_MYCTO]] Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate (dTTP) synthesis, is essential for DNA synthesis and cellular growth (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: DTMP kinase]] | ||
| + | [[Category: Gingell, H]] | ||
[[Category: Hussein, S]] | [[Category: Hussein, S]] | ||
| + | [[Category: Read, J A]] | ||
[[Category: Tucker, J]] | [[Category: Tucker, J]] | ||
| - | [[Category: | + | [[Category: Kinase]] |
| - | [[Category: | + | [[Category: Transferase]] |
Revision as of 13:46, 14 January 2015
Mtb TMK in complex with compound 34
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Categories: DTMP kinase | Gingell, H | Hussein, S | Read, J A | Tucker, J | Kinase | Transferase
