4uu6
From Proteopedia
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| - | ''' | + | ==CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1== |
| - | + | <StructureSection load='4uu6' size='340' side='right' caption='[[4uu6]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4uu6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UU6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UU6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uu5|4uu5]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uu6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uu6 RCSB], [http://www.ebi.ac.uk/pdbsum/4uu6 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: Ivanova, M | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/MPP5_HUMAN MPP5_HUMAN]] May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity). |
| - | [[Category: Purkiss, A | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Ivanova, M E]] | ||
| + | [[Category: McDonald, N Q]] | ||
| + | [[Category: Purkiss, A G]] | ||
| + | [[Category: Structural protein]] | ||
Revision as of 13:46, 14 January 2015
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1
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