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4uym

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'''Unreleased structure'''
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==Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with voriconazole==
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<StructureSection load='4uym' size='340' side='right' caption='[[4uym]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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The entry 4uym is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4uym]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UYM FirstGlance]. <br>
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Authors: Hargrove, T.Y., Wawrzak, Z., Lepesheva, G.I.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=VOR:VORICONAZOLE'>VOR</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uyl|4uyl]]</td></tr>
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Description: Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with voriconazole
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uym OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uym RCSB], [http://www.ebi.ac.uk/pdbsum/4uym PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Sterol 14-demethylase]]
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[[Category: Hargrove, T Y]]
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[[Category: Lepesheva, G I]]
[[Category: Wawrzak, Z]]
[[Category: Wawrzak, Z]]
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[[Category: Hargrove, T.Y]]
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[[Category: Cytochrome p450]]
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[[Category: Lepesheva, G.I]]
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[[Category: Cytochrome p450 fold]]
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[[Category: Endoplasmic reticulum membrane]]
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[[Category: Eukaryotic membrane]]
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[[Category: Heme]]
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[[Category: Monooxygenase]]
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[[Category: Oxidoreductase]]
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[[Category: Sterol biosynthesis]]

Revision as of 12:24, 20 August 2015

Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with voriconazole

4uym, resolution 2.55Å

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