4v0z

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'''Unreleased structure'''
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==o-nitrophenyl Cellobioside as an Active Site Probe for Family 7 Cellobiohydrolases==
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<StructureSection load='4v0z' size='340' side='right' caption='[[4v0z]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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The entry 4v0z is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4v0z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichoderma_reesei_qm9414 Trichoderma reesei qm9414]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V0Z FirstGlance]. <br>
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Authors: Nutt, A., Momeni, M.H., Stahlberg, J.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OPO:O-NITROPHENOL'>OPO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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Description: o-nitrophenyl Cellobioside as an Active Site Probe for Family 7 Cellobiohydrolases
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(reducing_end) Cellulose 1,4-beta-cellobiosidase (reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.176 3.2.1.176] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v0z OCA], [http://pdbe.org/4v0z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4v0z RCSB], [http://www.ebi.ac.uk/pdbsum/4v0z PDBsum]</span></td></tr>
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[[Category: Momeni, M.H]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GUX1_HYPJE GUX1_HYPJE]] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
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__TOC__
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</StructureSection>
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[[Category: Trichoderma reesei qm9414]]
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[[Category: Momeni, M H]]
[[Category: Nutt, A]]
[[Category: Nutt, A]]
[[Category: Stahlberg, J]]
[[Category: Stahlberg, J]]
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[[Category: Carbohydrate metabolism]]
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[[Category: Cellulose degradation]]
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[[Category: Glycoprotein]]
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[[Category: Glycosidase]]
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[[Category: Glycoside hydrolase]]
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[[Category: Hydrolase]]
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[[Category: Hypocrea jecorina]]
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[[Category: Polysaccharide degradation]]
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[[Category: Pyrrolidone carboxylic acid]]

Revision as of 14:39, 30 September 2015

o-nitrophenyl Cellobioside as an Active Site Probe for Family 7 Cellobiohydrolases

4v0z, resolution 1.70Å

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