4w56
From Proteopedia
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| - | ''' | + | ==T4 Lysozyme L99A with sec-Butylbenzene Bound== |
| - | + | <StructureSection load='4w56' size='340' side='right' caption='[[4w56]], [[Resolution|resolution]] 1.63Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4w56]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W56 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3GY:(2R)-BUTAN-2-YLBENZENE'>3GY</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w56 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w56 RCSB], [http://www.ebi.ac.uk/pdbsum/4w56 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lysozyme]] | ||
[[Category: Eidam, O]] | [[Category: Eidam, O]] | ||
| + | [[Category: Fischer, M]] | ||
| + | [[Category: Merski, M]] | ||
| + | [[Category: Shoichet, B K]] | ||
| + | [[Category: Hydrolase]] | ||
Revision as of 13:21, 1 April 2015
T4 Lysozyme L99A with sec-Butylbenzene Bound
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Categories: Lysozyme | Eidam, O | Fischer, M | Merski, M | Shoichet, B K | Hydrolase
