1z1y
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 1z1y |SIZE=350|CAPTION= <scene name='initialview01'>1z1y</scene>, resolution 2.000Å | |PDB= 1z1y |SIZE=350|CAPTION= <scene name='initialview01'>1z1y</scene>, resolution 2.000Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=YB:YTTERBIUM (III) ION'>YB</scene> | + | |LIGAND= <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1y OCA], [http://www.ebi.ac.uk/pdbsum/1z1y PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1z1y RCSB]</span> | ||
}} | }} | ||
| Line 30: | Line 33: | ||
[[Category: Stowers, A W.]] | [[Category: Stowers, A W.]] | ||
[[Category: Su, H P.]] | [[Category: Su, H P.]] | ||
| - | [[Category: YB]] | ||
[[Category: four egf-like domain]] | [[Category: four egf-like domain]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:27:52 2008'' |
Revision as of 22:27, 30 March 2008
| |||||||
| , resolution 2.000Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax
Overview
P25 and P28 proteins are essential for Plasmodium parasites to infect mosquitoes and are leading candidates for a transmission-blocking malaria vaccine. The Plasmodium vivax P25 is a triangular prism that could tile the parasite surface. The residues forming the triangle are conserved in P25 and P28 from all Plasmodium species. A cocrystal structure shows that a transmission-blocking antibody uses only its heavy chain to bind Pvs25 at a vertex of the triangle.
About this Structure
1Z1Y is a Single protein structure of sequence from Plasmodium vivax. Full crystallographic information is available from OCA.
Reference
The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms., Saxena AK, Singh K, Su HP, Klein MM, Stowers AW, Saul AJ, Long CA, Garboczi DN, Nat Struct Mol Biol. 2006 Jan;13(1):90-1. Epub 2005 Dec 4. PMID:16327807
Page seeded by OCA on Mon Mar 31 01:27:52 2008
