4wb7

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'''Unreleased structure'''
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==Crystal structure of a chimeric fusion of human DnaJ (Hsp40) and cAMP-dependent protein kinase A (catalytic alpha subunit)==
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<StructureSection load='4wb7' size='340' side='right' caption='[[4wb7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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The entry 4wb7 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4wb7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WB7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WB7 FirstGlance]. <br>
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Authors: Cheung, J., Ginter, C., Cassidy, M., Franklin, M.C., Rudolph, M.J., Hendrickson, W.A.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
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Description:
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wb5|4wb5]], [[4wb6|4wb6]], [[4wb8|4wb8]]</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/cAMP-dependent_protein_kinase cAMP-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.11 2.7.11.11] </span></td></tr>
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[[Category: Ginter, C]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wb7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wb7 RCSB], [http://www.ebi.ac.uk/pdbsum/4wb7 PDBsum]</span></td></tr>
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[[Category: Rudolph, M.J]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DNJB1_HUMAN DNJB1_HUMAN]] Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP.
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__TOC__
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</StructureSection>
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[[Category: CAMP-dependent protein kinase]]
[[Category: Cassidy, M]]
[[Category: Cassidy, M]]
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[[Category: Franklin, M.C]]
 
[[Category: Cheung, J]]
[[Category: Cheung, J]]
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[[Category: Hendrickson, W.A]]
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[[Category: Franklin, M C]]
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[[Category: Ginter, C]]
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[[Category: Hendrickson, W A]]
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[[Category: Rudolph, M J]]
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[[Category: Adenosine triphosphate]]
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[[Category: Catalysis]]
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[[Category: Chaperone]]
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[[Category: Chimera]]
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[[Category: Fibrolamellar hepatocellular carinoma]]
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[[Category: Fusion]]
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[[Category: Phosphorylation]]
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[[Category: Protein kinase]]

Revision as of 17:00, 21 January 2015

Crystal structure of a chimeric fusion of human DnaJ (Hsp40) and cAMP-dependent protein kinase A (catalytic alpha subunit)

4wb7, resolution 1.90Å

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