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3k56
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IPP beta-S== | ==Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IPP beta-S== | ||
<StructureSection load='3k56' size='340' side='right' caption='[[3k56]], [[Resolution|resolution]] 2.34Å' scene=''> | <StructureSection load='3k56' size='340' side='right' caption='[[3k56]], [[Resolution|resolution]] 2.34Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3k56]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3k56]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K56 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IS3:ISOPENTENYL+DIPHOSPHATE+BETA-S'>IS3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IS3:ISOPENTENYL+DIPHOSPHATE+BETA-S'>IS3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3k4o|3k4o]], [[3k4y|3k4y]], [[3k52|3k52]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3k4o|3k4o]], [[3k4y|3k4y]], [[3k52|3k52]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0044 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0044 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k56 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k56 RCSB], [http://www.ebi.ac.uk/pdbsum/3k56 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k56 OCA], [http://pdbe.org/3k56 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k56 RCSB], [http://www.ebi.ac.uk/pdbsum/3k56 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k56 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/IPK_METJA IPK_METJA]] Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate.<ref>PMID:16621811</ref> <ref>PMID:20392112</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k56 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3k56" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Atcc 43067]] |
[[Category: Dellas, N]] | [[Category: Dellas, N]] | ||
[[Category: Noel, J P]] | [[Category: Noel, J P]] | ||
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[[Category: Isopentenyl monophosphate]] | [[Category: Isopentenyl monophosphate]] | ||
[[Category: Isoprenoid biosynthesis]] | [[Category: Isoprenoid biosynthesis]] | ||
| + | [[Category: Methanocaldococcus jannaschii]] | ||
[[Category: Mevalonate pathway]] | [[Category: Mevalonate pathway]] | ||
[[Category: Small molecule kinase]] | [[Category: Small molecule kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 21:15, 4 August 2016
Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IPP beta-S
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