4woz

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'''Unreleased structure'''
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==Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine==
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<StructureSection load='4woz' size='340' side='right' caption='[[4woz]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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The entry 4woz is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4woz]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WOZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WOZ FirstGlance]. <br>
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Authors: Liu, W.D., Guo, R.T., Cui, Y.F., Chen, X., Wu, Q.Q., Zhu, D.M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN9:2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE'>MN9</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylneuraminate_lyase N-acetylneuraminate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.3 4.1.3.3] </span></td></tr>
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Description: Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4woz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4woz OCA], [http://pdbe.org/4woz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4woz RCSB], [http://www.ebi.ac.uk/pdbsum/4woz PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Cui, Y.F]]
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== Function ==
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[[Category: Zhu, D.M]]
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[[http://www.uniprot.org/uniprot/D5Q364_PEPDI D5Q364_PEPDI]] Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.[HAMAP-Rule:MF_01237][SAAS:SAAS00160136]
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[[Category: Wu, Q.Q]]
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__TOC__
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</StructureSection>
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[[Category: N-acetylneuraminate lyase]]
[[Category: Chen, X]]
[[Category: Chen, X]]
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[[Category: Liu, W.D]]
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[[Category: Cui, Y F]]
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[[Category: Guo, R.T]]
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[[Category: Guo, R T]]
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[[Category: Liu, W D]]
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[[Category: Wu, Q Q]]
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[[Category: Zhu, D M]]
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[[Category: Aldolase]]
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[[Category: Lyase]]
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[[Category: Thermostable]]

Revision as of 05:30, 22 October 2015

Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine

4woz, resolution 1.96Å

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