This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4woz
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine== |
| - | + | <StructureSection load='4woz' size='340' side='right' caption='[[4woz]], [[Resolution|resolution]] 1.96Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4woz]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WOZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WOZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN9:2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE'>MN9</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylneuraminate_lyase N-acetylneuraminate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.3 4.1.3.3] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4woz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4woz OCA], [http://pdbe.org/4woz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4woz RCSB], [http://www.ebi.ac.uk/pdbsum/4woz PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/D5Q364_PEPDI D5Q364_PEPDI]] Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.[HAMAP-Rule:MF_01237][SAAS:SAAS00160136] |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: N-acetylneuraminate lyase]] | ||
[[Category: Chen, X]] | [[Category: Chen, X]] | ||
| - | [[Category: | + | [[Category: Cui, Y F]] |
| - | [[Category: Guo, R | + | [[Category: Guo, R T]] |
| + | [[Category: Liu, W D]] | ||
| + | [[Category: Wu, Q Q]] | ||
| + | [[Category: Zhu, D M]] | ||
| + | [[Category: Aldolase]] | ||
| + | [[Category: Lyase]] | ||
| + | [[Category: Thermostable]] | ||
Revision as of 05:30, 22 October 2015
Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
| |||||||||||
Categories: N-acetylneuraminate lyase | Chen, X | Cui, Y F | Guo, R T | Liu, W D | Wu, Q Q | Zhu, D M | Aldolase | Lyase | Thermostable
