4wpd
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==X-ray Crystal Structure of CYP119 complexed with 4-(4-flourophenyl)-1H-imidazole== |
| - | + | <StructureSection load='4wpd' size='340' side='right' caption='[[4wpd]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4wpd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WPD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3SQ:4-(4-FLUOROPHENYL)-1H-IMIDAZOLE'>3SQ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tt5|4tt5]], [[4tuv|4tuv]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wpd RCSB], [http://www.ebi.ac.uk/pdbsum/4wpd PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CP119_SULAC CP119_SULAC]] The endogenous substrate is not known. In vitro, catalyzes the H(2)O(2)-dependent epoxidation of styrene, cis-beta-methylstyrene, and cis-stilbene with retention of stereochemistry. Is able to use cumene hydroperoxide (CHP) or tert-butyl hydroperoxide (TBHP) instead of H(2)O(2) as the electron acceptor. Can also hydroxylate fatty acids such as lauric acid.<ref>PMID:10799487</ref> <ref>PMID:12010041</ref> <ref>PMID:18157853</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Madrona, Y]] | [[Category: Madrona, Y]] | ||
| + | [[Category: Cytochrome p450]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 13:11, 18 February 2015
X-ray Crystal Structure of CYP119 complexed with 4-(4-flourophenyl)-1H-imidazole
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