4wpu
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP== | |
| + | <StructureSection load='4wpu' size='340' side='right'caption='[[4wpu]], [[Resolution|resolution]] 2.26Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4wpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WPU FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wiu|4wiu]], [[4wpt|4wpt]], [[4wou|4wou]], [[4wpv|4wpv]], [[4wie|4wie]], [[4wl8|4wl8]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pckG, MRA_0219 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419947 MYCTA])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpu OCA], [http://pdbe.org/4wpu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wpu RCSB], [http://www.ebi.ac.uk/pdbsum/4wpu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wpu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PCKG_MYCTA PCKG_MYCTA]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | ||
| - | + | ==See Also== | |
| - | + | *[[Phosphoenolpyruvate carboxykinase|Phosphoenolpyruvate carboxykinase]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mycta]] |
| + | [[Category: Kim, H L]] | ||
| + | [[Category: Sacchettini, J C]] | ||
| + | [[Category: Anaplerotic reaction]] | ||
| + | [[Category: Gtp-dependent pepck]] | ||
| + | [[Category: Lyase]] | ||
| + | [[Category: Omega-loop]] | ||
| + | [[Category: P-loop]] | ||
| + | [[Category: R-loop]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:26, 23 May 2019
Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP
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