4wyk

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'''Unreleased structure'''
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==Structure of the LRR and NTF2-like domains of NXF1 complexed with NXT1==
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<StructureSection load='4wyk' size='340' side='right' caption='[[4wyk]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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The entry 4wyk is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4wyk]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WYK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WYK FirstGlance]. <br>
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Authors: Aibara, S., Valkov, E., Stewart, M.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wyk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wyk RCSB], [http://www.ebi.ac.uk/pdbsum/4wyk PDBsum]</span></td></tr>
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</table>
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Description: Structure of the LRR and NTF2-like domains of NXF1 complexed with NXT1
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== Function ==
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[[Category: Unreleased Structures]]
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[[http://www.uniprot.org/uniprot/NXF1_HUMAN NXF1_HUMAN]] Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5.<ref>PMID:9660949</ref> <ref>PMID:19165146</ref> [[http://www.uniprot.org/uniprot/NXT1_HUMAN NXT1_HUMAN]] Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5.<ref>PMID:10567585</ref> <ref>PMID:10848583</ref> <ref>PMID:11259602</ref> <ref>PMID:19165146</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Aibara, S]]
[[Category: Aibara, S]]
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[[Category: Valkov, E]]
 
[[Category: Stewart, M]]
[[Category: Stewart, M]]
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[[Category: Valkov, E]]
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[[Category: Nuclear export]]
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[[Category: Transport protein]]

Revision as of 16:01, 7 February 2015

Structure of the LRR and NTF2-like domains of NXF1 complexed with NXT1

4wyk, resolution 3.40Å

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