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4x1j
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==X-ray crystal structure of the dimeric BMP antagonist NBL1== |
| - | + | <StructureSection load='4x1j' size='340' side='right' caption='[[4x1j]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x1j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X1J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jph|4jph]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x1j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x1j RCSB], [http://www.ebi.ac.uk/pdbsum/4x1j PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NBL1_HUMAN NBL1_HUMAN]] Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Kattamuri, C]] | [[Category: Kattamuri, C]] | ||
[[Category: Nolan, K]] | [[Category: Nolan, K]] | ||
| - | [[Category: Thompason, T | + | [[Category: Thompason, T B]] |
| + | [[Category: Bmp antagonist]] | ||
| + | [[Category: Bmp binding protein]] | ||
| + | [[Category: Cystine-knot]] | ||
| + | [[Category: Dan family]] | ||
Revision as of 13:49, 14 January 2015
X-ray crystal structure of the dimeric BMP antagonist NBL1
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