1z1x

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<table><tr><td colspan='2'>[[1z1x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z1X FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z1x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z1X FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rmr|1rmr]], [[1tej|1tej]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rmr|1rmr]], [[1tej|1tej]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z1x RCSB], [http://www.ebi.ac.uk/pdbsum/1z1x PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1x OCA], [http://pdbe.org/1z1x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z1x RCSB], [http://www.ebi.ac.uk/pdbsum/1z1x PDBsum]</span></td></tr>
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</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DIS_ECHCA DIS_ECHCA]] Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1) (By similarity).
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[[http://www.uniprot.org/uniprot/DID_ECHCA DID_ECHCA]] Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 07:33, 10 September 2015

Crystal Structure of a novel disintegrin from Saw-scaled viper at 3.2 A resolution

1z1x, resolution 3.20Å

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