4xcx

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'''Unreleased structure'''
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==METHYLTRANSFERASE DOMAIN OF SMALL RNA 2'-O-METHYLTRANSFERASE==
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<StructureSection load='4xcx' size='340' side='right' caption='[[4xcx]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
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The entry 4xcx is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4xcx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XCX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XCX FirstGlance]. <br>
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Authors: Walker, J.R., Zeng, H., Dong, A., Li, Y., Wernimont, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Wu, H., STRUCTURAL GENOMICS CONSORTIUM (SGC)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xcx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xcx RCSB], [http://www.ebi.ac.uk/pdbsum/4xcx PDBsum]</span></td></tr>
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Description: METHYLTRANSFERASE DOMAIN OF SMALL RNA 2'-O-METHYLTRANSFERASE
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[http://www.uniprot.org/uniprot/HENMT_HUMAN HENMT_HUMAN]] Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Brown, P J]]
[[Category: Dong, A]]
[[Category: Dong, A]]
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[[Category: Edwards, A M]]
[[Category: Li, Y]]
[[Category: Li, Y]]
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[[Category: Zeng, H]]
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[[Category: Structural genomic]]
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[[Category: Walker, J R]]
[[Category: Wernimont, A]]
[[Category: Wernimont, A]]
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[[Category: Walker, J.R]]
 
[[Category: Wu, H]]
[[Category: Wu, H]]
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[[Category: Bountra, C]]
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[[Category: Zeng, H]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Methyltransferase]]
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[[Category: Brown, P.J]]
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[[Category: Sah]]
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[[Category: Edwards, A.M]]
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[[Category: Sgc]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Transferase]]

Revision as of 13:49, 14 January 2015

METHYLTRANSFERASE DOMAIN OF SMALL RNA 2'-O-METHYLTRANSFERASE

4xcx, resolution 2.84Å

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